Siri Enger Selected Research

Procyclidine (Procyclidine Hydrochloride)

9/2015	Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats.
1/2014	Behavioral side effects of prophylactic therapies against soman-induced seizures and lethality in rats.
12/2013	Two medical therapies very effective shortly after high levels of soman poisoning in rats, but only one with universal utility.
10/2013	Capacities of metabotropic glutamate modulators in counteracting soman-induced seizures in rats.
12/2011	Enhanced efficacy of anticonvulsants when combined with levetiracetam in soman-exposed rats.
1/2010	Roles of perirhinal and posterior piriform cortices in control and generation of seizures: a microinfusion study in rats exposed to soman.
2/2008	Anticonvulsant efficacy of drugs with cholinergic and/or glutamatergic antagonism microinfused into area tempestas of rats exposed to soman.
10/2006	Pharmacological therapies against soman-induced seizures in rats 30 min following onset and anticonvulsant impact.
2/2006	Efficacy of immediate and subsequent therapies against soman-induced seizures and lethality in rats.

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Siri Enger Research Topics

Disease

16	Seizures (Absence Seizure) 09/2015 - 02/2006
4	Poisoning 09/2015 - 08/2013
2	Cognitive Dysfunction 01/2014 - 06/2008
1	Epilepsy (Aura) 12/2011
1	Tonic-Clonic Epilepsy (Epilepsy, Tonic Clonic) 02/2008
1	Weight Loss (Weight Reduction) 07/2007
1	Body Weight (Weight, Body) 07/2007

Drug/Important Bio-Agent (IBA)

14	SomanIBA 09/2015 - 02/2006
13	Anticonvulsants (Antiepileptic Drugs)IBA 09/2015 - 02/2006
9	Procyclidine (Procyclidine Hydrochloride)FDA Link 09/2015 - 02/2006
8	Nerve AgentsIBA 09/2015 - 08/2006
4	asoxime chloride (H16)IBA 09/2015 - 02/2006
4	caramiphenIBA 12/2011 - 02/2008
3	Levetiracetam (Keppra)FDA LinkGeneric 09/2015 - 12/2011
3	PhysostigmineIBA 01/2014 - 06/2008
3	Pentobarbital (Nembutal)FDA Link 10/2006 - 02/2006
2	Scopolamine (Hyoscine)FDA Link 12/2013 - 01/2010
2	2-(2,3-dicarboxycyclopropyl)glycineIBA 10/2013 - 06/2010
2	2,3- dioxo- 6- nitro- 7- sulfamoylbenzo(f)quinoxaline (NBQX)IBA 12/2011 - 01/2010
2	Ketamine FDA LinkGeneric 12/2011 - 01/2010
2	MuscimolIBA 12/2011 - 01/2010
2	Cholinergic Agents (Cholinergics)IBA 01/2010 - 06/2008
2	Diazepam (Valium)FDA LinkGeneric 10/2006 - 02/2006
2	Propofol (Diprivan)FDA LinkGeneric 10/2006 - 08/2006
1	VX (EDIM)IBA 09/2015
1	tabunIBA 09/2015
1	OximesIBA 09/2015
1	SarinIBA 09/2015
1	cyclohexyl methylphosphonofluoridate (cyclosarin)IBA 09/2015
1	Glutamic Acid (Glutamate)FDA Link 10/2013
1	MecamylamineIBA 12/2011
1	Cytidine Monophosphate (CMP)IBA 12/2011
1	Pyridostigmine Bromide (Pyridostigmine)FDA LinkGeneric 12/2011
1	alpha-methyl-4-carboxyphenylglycineIBA 06/2010
1	AcidsIBA 06/2010
1	Excitatory Amino Acid AntagonistsIBA 06/2010
1	Cholinergic Antagonists (Anticholinergics)IBA 05/2010
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 05/2010
1	AMPA Receptors (AMPA Receptor)IBA 01/2010
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2010
1	BenactyzineIBA 06/2008
1	Antiparkinson Agents (Antiparkinsonian Agents)IBA 06/2008
1	Trihexyphenidyl (Artane)FDA LinkGeneric 06/2008
1	salicylhydroxamic acid (SHAM)IBA 07/2007
1	gamma-Aminobutyric Acid (GABA)IBA 08/2006
1	Ethanol (Ethyl Alcohol)IBA 08/2006
1	pro-diazepam (avizafone)IBA 02/2006
1	Atropine FDA LinkGeneric 02/2006

Therapy/Procedure

5	Therapeutics 09/2015 - 02/2006
1	Intramuscular Injections 02/2006